Rare Pulmonology News
Advertisement
5 Facts you should know about
Spinal muscular atrophy (SMA)
1
The term spinal muscular atrophy (SMA) refers to a group of genetic disorders all characterized by degeneration of anterior horn cells and resultant muscle atrophy and weakness
2
The severity of SMA is highly variable and the clinical features can be classified into 4 main phenotypes on the basis of age of onset and maximum motor function achieved
3
The clinical severity of SMA correlates inversely with SMN2 gene copy number and varies from extreme weakness and paraplegia of infancy to a mild proximal weakness of adulthood
4
The incidence of SMA in the United States is 1:10,000/11,000 live births
5
SMA affects individuals of all ethnic groups
Rare Pulmonology News
Advertisement